High Sensitivity Immunomagnetic CTC Isolation as Compared to Alternative Isolation Methods

Introduction

The high sensitivity IsoFlux System enables a wide range of downsream molecular studies using CTCs. The increased sensitivity leads to a greater percentage of patients across all carcinoma indications (>80%), that can have enough CTCs collected for analysis. Additonaly, Fluxion has validated several downstream assays that can be used with IsoFlux CTC samples. One example is a mutational profiling assay for common oncogene targets (KRAS, BRAF, EGFR, etc.) that uses a standard qPCR instrument.

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